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Fluorescence images, obtained through confocal microscopy, of A2780/S and SKOV-3 cells treated with complexes 1a and 2a , at a concentration of 10 µM for 20 min.

Journal: Frontiers in Chemistry

Article Title: Thiosugar-functionalized gold(I)-NHC complexes as selective anticancer agents for potential targeted therapy

doi: 10.3389/fchem.2026.1724206

Figure Lengend Snippet: Fluorescence images, obtained through confocal microscopy, of A2780/S and SKOV-3 cells treated with complexes 1a and 2a , at a concentration of 10 µM for 20 min.

Article Snippet: A2780 human ovarian cancer cell line was purchased from Creative Bioarray (NY 11967, United States): A2780/S sensitive to cisplatin (Lot N° CSC-C9491J) and A2780/R resistant to cisplatin (Lot N° CSC-C9492J); SKOV-3 human ovarian cancer cell line purchased from Cell Lines Service GmbH (Germany) (Lot 300342-1420SF), and normal human skeletal myoblasts (HSkMC) was purchased from Thermo Fisher Scientific Inc (Lot N° 2007603).

Techniques: Fluorescence, Confocal Microscopy, Concentration Assay

FACS results for the complexes 1a , 2a , 1b , 2b in the A2780/S cell line (left) and the A2780/R cell line (right).

Journal: Frontiers in Chemistry

Article Title: Thiosugar-functionalized gold(I)-NHC complexes as selective anticancer agents for potential targeted therapy

doi: 10.3389/fchem.2026.1724206

Figure Lengend Snippet: FACS results for the complexes 1a , 2a , 1b , 2b in the A2780/S cell line (left) and the A2780/R cell line (right).

Article Snippet: A2780 human ovarian cancer cell line was purchased from Creative Bioarray (NY 11967, United States): A2780/S sensitive to cisplatin (Lot N° CSC-C9491J) and A2780/R resistant to cisplatin (Lot N° CSC-C9492J); SKOV-3 human ovarian cancer cell line purchased from Cell Lines Service GmbH (Germany) (Lot 300342-1420SF), and normal human skeletal myoblasts (HSkMC) was purchased from Thermo Fisher Scientific Inc (Lot N° 2007603).

Techniques:

Median fluorescence intensity of A2780/S cells after co-treatment with the fluorescent compounds 1a , 1b , 2a , 2b and GLUT-1 inhibitor. Histograms with identical letters on the top are not significantly different, not having a P -value <0.05, according to the LSD post hoc test.

Journal: Frontiers in Chemistry

Article Title: Thiosugar-functionalized gold(I)-NHC complexes as selective anticancer agents for potential targeted therapy

doi: 10.3389/fchem.2026.1724206

Figure Lengend Snippet: Median fluorescence intensity of A2780/S cells after co-treatment with the fluorescent compounds 1a , 1b , 2a , 2b and GLUT-1 inhibitor. Histograms with identical letters on the top are not significantly different, not having a P -value <0.05, according to the LSD post hoc test.

Article Snippet: A2780 human ovarian cancer cell line was purchased from Creative Bioarray (NY 11967, United States): A2780/S sensitive to cisplatin (Lot N° CSC-C9491J) and A2780/R resistant to cisplatin (Lot N° CSC-C9492J); SKOV-3 human ovarian cancer cell line purchased from Cell Lines Service GmbH (Germany) (Lot 300342-1420SF), and normal human skeletal myoblasts (HSkMC) was purchased from Thermo Fisher Scientific Inc (Lot N° 2007603).

Techniques: Fluorescence